Rational Use of Cholinesterase Activity Testing in Pesticide Poisoning

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Rational use of cholinesterase activity testing in pesticide poisoning.

BACKGROUND The use of acetylcholinesterase (AChE) activity testing in pesticide poisoning often falls on family physicians when evaluating a suspected poisoning or when monitoring the health of pesticide applicators. METHODS A review of the literature and consideration of three illustrative cases shows misunderstandings in the pathophysiology of the enzyme and in procedures for effective test...

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Cholinesterase Research Outreach Project (CROP): measuring cholinesterase activity and pesticide use in an agricultural community

BACKGROUND Australian farmers and their workers are exposed to a wide variety of pesticides. Organophosphate (OP) insecticides are a widely used class of pesticide used for animal husbandry practices (Naphthalophos for sheep dipping, jetting and drench), crop production for pest control (Dimethoate) and in public health (Maldison for head lice). Acute poisonings with this class of insecticide a...

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The mode of recovery of cholinesterase activity in vivo after organophosphorus poisoning. 1. Erythrocyte cholinesterase.

Moerner, A. H. (1895). Skand. Arch. Phy8iol. 6, 332. Patte, J. C., Baldassaire, G. & Loret, J. (1958). Rev. franf. Eud. clin. biol. 3, 960. Peterson, H. A. & Sober, E. A. (1958). Fed. Proc. 17, 288. Popenoe, E. A. (1955). J. biol. Chem. 217, 61. Porter, K. R. & Tamm, I. (1955). J. biol. Chem. 212, 135. Prasad, A. S. & Flink, E. B. (1958). J. Lab. clin. Med. 51, 345. Rich, C. & DiFerrante, N. (1...

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The mode of recovery of cholinesterase activity in vivo after organophosphorus poisoning. 2. Brain cholinesterase.

Previous investigators (Frawley, Hagan & Fitzhugh, 1952; Davison, 1955; Kewitz & Nachmansohn, 1957) have observed that the rate of recovery in vivo of inhibited brain true cholinesterase depended on which inhibitor was used. With diiwopropyl phosphorofluoridate (Frawley et al. 1952; Davison, 1955; Kewitz & Nachmansobn, 1957) recovery was slow, whereas with tetraethyl pyrophosphate (Davison, 195...

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Pesticide Poisoning in Humans

The ever increasing demand for more food production has been met by adoption of better crop protection measures. Since world war II synthetic chemicals/poisons have been extensively used for the control of agricultural as well as household and medical insect pests. These poisons which otherwise are employed for human benefit can also be called as economic poisons. Pesticides used for the contro...

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ژورنال

عنوان ژورنال: The Journal of the American Board of Family Medicine

سال: 1999

ISSN: 1557-2625,1558-7118

DOI: 10.3122/jabfm.12.4.307